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Taken together, our results indicate Caspase-Glo 1 inflammasome and NanoBRET target engagement NLRP3 assays serve as great cell-based assay platforms to facilitate inflammasome
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Therapeutically relevant cell-based assays for drug discovery and development Cell-based assays provide a relevant biological context, making them crucial for discovery and development. Our
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Abstract With the biological relevance of the whole cells, low cost compared with animal experiments, a wide variety of cell-based screening platforms (cell-based assay, cell-based
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Despite being attractive and druggable targets, the majority of SLCs remains understudied. One major hurdle in research on SLCs is the lack of tools, such as cell-based assays
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Understanding how living cells respond to external stimuli is the backbone of modern biomedical research. Cell based assays serve as the bridge between raw biological insight and
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